Adenylate Cyclase Toxins

Cyclic AMP is a ubiquitous messenger that integrates many processes of the cell. Diverse families of adenylate cyclases and phosphodiesterases stringently regulate the intracellular concentration of cAMP. Any alteration in the cytosolic concentration of cAMP has a profound effect on the various processes of the cell. Disruption of these cellular processes in vivo is often the most critical event in the pathogenesis of infectious diseases for animals and humans. Many pathogenic bacteria secrete toxins to alter the intracellular concentration of cAMP. These toxins either disrupt the normal regulation of the host cell’s adenylate cyclases/phosphodiesterases or they themselves catalyze the synthesis of cAMP in the host cell. The latter are known as the adenylate cyclase toxins. Four such toxins have been identified: the invasive adenylate cyclase of Bordetella pertussis, the edema factor of Bacillus anthracis, ExoY of Pseudomonas aeruginosa, and the adenylate cyclase of Yersinia pestis. These adenylate cyclase toxins enter the eukaryotic host cells and get activated by eukaryotic cofactors, like calmodulin, to trigger the synthesis of cAMP in these cells. By accumulating cAMP in the target cells, these toxins either modulate the cellular function or completely deactivate the cell for further function. The immune effector cells appear to be the primary target of these adenylate cyclase toxins. By accumulating cAMP in the immune effector cells, these adenylate cyclase toxins poison the immune system and thus facilitate the survival of the bacteria in the host.

Hemp Edestin agglutinates bacteria and virus from the body.


The adenylate cyclase toxins.



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Saved my life with Cannabis Activated Retrograde Synaptic Signaling (CARSS), Hemmaggluting bacteria, and virus-hosting bacteria from my CONSUMPTIVE WASTE by EATING HEMP SEED, SWITCHING on my CARSS-CB2 Receptors WITH Beta-Caryophyllene, (a CBD-Like CB2 Receptor Agonist, and the FIRST CANNABINOID Approved by FDA in 1964), and my CARSS-CB1 Receptors to suppress the TRAUMA of the digestive dis-order has caused WITH THC! Then reverse engineered the process to learn about CARSS, the Body’s OWN Regulation and Modulation system and how the Human system works with Cannabis and Hemp to relieve Chronic Conditions.