Cannabisin B induces autophagic cell death by inhibiting the AKT/mTOR pathway and S phase cell cycle arrest in HepG2 cells.

"This study investigates the anticancer properties of cannabisin B, purified from hempseed hull, in HepG2 human hepatoblastoma cells. The results indicate that cannabisin B significantly inhibited cell proliferation by inducing autophagic cell death rather than typical apoptosis." "These findings suggest that cannabisin B possesses considerable antiproliferative activity and that it may

Cannabis removes Alzheimer’s-related protein from nerve cells

Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids The beta amyloid (Aβ) and other aggregating proteins in the brain increase with age and are frequently found within neurons. The mechanistic relationship between intracellular amyloid, aging and neurodegeneration is not, however, well understood. We use a proteotoxicity model based upon the

State of Cannabis: Indiana

State of Cannabis: Indiana By Daniel Shortt on June 12, 2016 POSTED IN ADVOCACY, HEMP, STATES This is proving to be a big year for cannabis. As a result, we are ranking the fifty states from worst to best on how they treat cannabis and those who consume it. Each of our State of Cannabis

Tennessee Farmers Backing Away From Hemp Farming After 2015 Struggles?

If we are to believe 322 Farmer Mason... Tennessee Farmers Backing Away From Hemp Farming After 2015 Struggles MARCH 22, 2016 10:00 AM "Many Tennessee farmers who participated in the state's return to industrial hemp farming are not planning on growing the highly regulated seed this year, saying it wasn't profitable last year,

Scientists Discover that the Breathtaking Ellora Caves Have Been Preserved by Hemp

According to Singh, “[c]annabis sativa, popularly known as ganja or bhang, was found mixed in the clay and lime plaster at Ellora. This was confirmed by technologies such as scanning of the electron microscope, Fourier transform, infra-red spectroscopy and stereo-microscopic studies.”  Singh and Sardesai explained the preservative qualities of the

3rd-Party Governor?

Will Indiana voters be blessed with an Andrew Horning run for Indiana Governor?  Or are we stuck with the same Right-Wing and Left-Wing that was slated in 2012? Andrew is one of the most equitable politicians to ever grace the people.  Indiana is blessed with such a legal and constitutional scholar and